I just had to get this one. I found this last week during the members night at Chicago's Adler Planetarium.
The people that I were with of course knew that this is referring to "force", but they didn't get the connection. So I had to explain to them that Newton's 2nd law, i.e. F=ma can be expressed in a more general form, i.e. F = dp/dt, where p is momentum mv. Thus
F = d/dt (mv)
Of course, I'm not surprised that most people, and probably most of Adler's visitors, would not get this unless they know a bit of calculus and have done general physics with calculus. Maybe that was why this t-shirt was on sale! :)
Maybe I'll wear this when I teach kinematics this Fall!