When young scientists "first start becoming acquainted with what it means to do research in the private sector, it's really quite a culture shock," says Michael A. Santoro, a business ethics professor at Rutgers Business School in New Jersey. "In business, everything begins with the profit motive. ... Just the very idea of research is geared towards a product rather than knowledge itself. The most critical factor in determining whether a scientist is going to be successful in making the transition from the university to the private sector is the ability to buy into that point of view."
A good article to read if you about to enter the job market at any level.